API · /genetics-api

Population Genetics API

healthy 3,334 Subscribers

Population-genetics maths as an API, computed locally and deterministically. The hardy-weinberg endpoint applies the Hardy-Weinberg principle, p² + 2pq + q² = 1 — give a dominant allele frequency p, a recessive q, or the homozygous-recessive (affected) frequency q² and it returns all the allele and genotype frequencies, including the carrier frequency 2pq. The punnett endpoint crosses two parent genotypes and returns the offspring genotype and phenotype ratios, handling a single gene (a monohybrid 1:2:1 / 3:1 cross), two genes (a dihybrid 9:3:3:1 cross) and up to four genes by independent assortment. The carrier endpoint takes the incidence of a recessive disease — as a fraction or one-in-N — and returns the recessive allele frequency q = √incidence, the carrier frequency 2pq, the one-in-N carrier rate and, for a given population, the expected number of carriers and affected individuals. Everything is computed locally and deterministically, so it is instant and private. Ideal for genetics-education, genetic-counselling, breeding and biology app developers, inheritance and risk tools, and biology teaching. Pure local computation — no key, no third-party service, instant. Live, nothing stored. 3 endpoints. This is population genetics; for DNA sequence analysis use a DNA API.

api.oanor.com/genetics-api
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Machine-readable spec so AI agents can integrate this API.

/api/genetics-api/openapi.json
/api/genetics-api/llms.txt

Discovery: GET /api/index.json lists every API.

Population Genetics API — live data on the oanor API marketplace

API health

healthy
Uptime
100.00%
Server probes · 24h
Avg latency
75 ms
Server probes · 24h
Subscribers
3,334
active
Total calls
76
last 7 days
status Full status page → · 8 probes/24h

Pricing

Pick a tier — billed monthly, cancel anytime.

Free

Free

  • 2,000 calls / month
  • 2 requests / second
  • Hard cap (429 above quota, no overage)
  • Hardy-Weinberg p2 + 2pq + q2 solver
  • Single Punnett square cross
  • Deterministic JSON results
  • Community support
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Starter

€5.00 /month

  • 25,000 calls / month
  • 5 requests / second
  • Hard cap (429 above quota, no overage)
  • All allele & genotype frequency endpoints
  • Monohybrid + dihybrid Punnett crosses
  • Equilibrium deviation check
  • Email support
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Pro

€15.00 /month

  • 150,000 calls / month
  • 15 requests / second
  • Hard cap (429 above quota, no overage)
  • Multi-allele population frequency batches
  • Chi-square HWE significance testing
  • Carrier & expected-ratio computations
  • Priority support
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Mega

€49.00 /month

  • 759,000 calls / month
  • 40 requests / second
  • Hard cap (429 above quota, no overage)
  • High-volume classroom & courseware access
  • Bulk cross + frequency batch endpoints
  • Highest rate limits for LMS integrations
  • Dedicated support SLA
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Built by

Related APIs

Other APIs with overlapping tags.

DNA Sequence API — oanor API marketplace

DNA Sequence API

DNA/RNA sequence-analysis maths as an API, computed locally and deterministically. The analyze endpoint reports the length and base composition of a sequence, the GC and AT content, the complement, the reverse and the reverse complement (the opposite strand read 5'→3'), and the approximate single-stranded molecular weight. The translate endpoint transcribes DNA to mRNA (T→U) and translates it to protein with the standard genetic code in reading frame 1, 2 or 3, giving the one-letter amino-acid sequence, the protein length and the number of stop codons. The melting endpoint estimates a primer's melting temperature with the Wallace rule, 4·(G+C) + 2·(A+T), for short oligos and a salt-adjusted basic formula for longer ones. Sequences are case- and whitespace-insensitive and accept A, C, G, T for DNA or U for RNA. Everything is computed locally and deterministically, so it is instant and private. Ideal for bioinformatics, molecular-biology, genomics and lab app developers, primer-design and sequence-inspection tools, and biology education. Pure local computation — no key, no third-party service, instant. Live, nothing stored. 3 endpoints. This is sequence analysis; for genome assembly data use a genomes API.

api.oanor.com/dna-api

Polygenic Scores API — oanor API marketplace

Polygenic Scores API

Polygenic (risk) scores as an API — powered by the NHGRI-EBI PGS Catalog, the open database of published polygenic scores: weighted combinations of genetic variants used to estimate a person's genetic predisposition to a trait or disease. Search traits by name to find their ontology ids, list every polygenic score developed for a trait, and read a score's full metadata — the reported and mapped (EFO/MONDO) traits, the number of variants in the score, the development method, genome build, the ancestry distribution of the samples it was built and evaluated on, the publication behind it (title, journal, date, PubMed id), the release date, license and a direct link to the scoring file. From breast cancer and coronary artery disease to type 2 diabetes and BMI, it is ideal for statistical genetics, genomics, risk-prediction research and bioinformatics tools. A polygenic-score / genetic-risk-prediction resource — distinct from single-variant association studies (GWAS Catalog), population allele frequencies (gnomAD) and clinical variant interpretation (ClinVar). Open data from the NHGRI-EBI PGS Catalog (CC BY 4.0).

api.oanor.com/pgs-api

GWAS Catalog API — oanor API marketplace

GWAS Catalog API

Human genetic trait associations as an API — powered by the NHGRI-EBI GWAS Catalog, the curated reference of published genome-wide association studies. It answers the core question of statistical genetics: which genetic variants (SNPs) are associated with which traits and diseases, and how strongly. Look up a SNP to get its functional class, genomic location and mapped genes; pull every trait association reported for it — the trait, p-value, effect size (odds ratio or beta), risk allele and frequency, and author-reported genes; and read the study behind the evidence — trait, sample sizes, ancestries, genotyping technology and the publication (PubMed id, authors, journal, date). From type 2 diabetes and Crohn disease to systemic lupus erythematosus and hundreds of thousands of associations, it is ideal for genomics, bioinformatics, statistical-genetics and biomedical research tools. A published genetic-association evidence base — distinct from population allele frequencies (gnomAD), clinical variant interpretation (ClinVar) and genome annotation (Ensembl). Open data from the NHGRI-EBI GWAS Catalog (EMBL-EBI).

api.oanor.com/gwas-api

ClinVar API — oanor API marketplace

ClinVar API

ClinVar as an API, powered by the US National Library of Medicine via NCBI E-utilities. ClinVar is the public archive of the relationships between human genetic variants and health, recording the clinical significance (interpretation) of each variant — whether it is Pathogenic, Likely pathogenic, of Uncertain significance, Likely benign or Benign — together with the conditions it is associated with. /v1/search?gene=BRCA1 searches ClinVar by gene symbol, or by free text with q= (e.g. a disease or HGVS expression), returning the total number of matching variants and a list of ClinVar variation ids. /v1/variant?id=4852102 returns a variant's summary: its ClinVar accession (VCV…), title, variant type, the variation and cDNA names, the clinical classification and review status, the associated condition(s), the gene(s) and primary gene, the chromosome and location, the protein change and the molecular consequence, plus a link to the ClinVar record. Get a variation id from /v1/search, then fetch its details. Ideal for clinical-genomics and variant-annotation pipelines, rare-disease and genetic-counselling tools, and research dashboards. Data from NCBI ClinVar (public domain). This is clinical variant interpretation — distinct from population allele-frequency databases (such as gnomAD) and from protein/sequence databases. Please keep request rates modest under NCBI fair-use.

api.oanor.com/clinvar-api

Frequently asked questions

Quick answers about pricing, quotas, and integration.

How do I get an API key for Population Genetics API?
Sign up for free at oanor.com, generate an API key from the developer dashboard, and call Population Genetics API with the x-oanor-key header. No credit card needed for the free tier.
What's the rate limit for Population Genetics API?
Free tier allows 1 request per second. Paid plans scale up to 50 requests per second on the Mega tier. Hard limits return HTTP 429 above the quota — no surprise overage charges.
How much does Population Genetics API cost?
Population Genetics API has a free tier with 100 calls / month. Paid plans start at €5.00 / month with higher quotas and faster rate limits.
Can I cancel my subscription anytime?
Yes. Plans are billed monthly and you can cancel anytime from your billing dashboard. No long-term contracts and no cancellation fee.
Is Population Genetics API GDPR-compliant?
All requests to Population Genetics API go through our EU-based gateway. Your upstream API key never leaves our server and no personal data is shared with the upstream provider beyond the request you send.

Pick an endpoint from the list on the left to see its details and try it.

Code snippets

Sign up to get an API key, then call any path under your slug.

curl https://api.oanor.com/genetics-api/SOME_PATH \
  -H "x-oanor-key: oanor_test_..."
const res = await fetch("https://api.oanor.com/genetics-api/SOME_PATH", {
  headers: { "x-oanor-key": "oanor_test_..." }
});
const data = await res.json();
$ch = curl_init("https://api.oanor.com/genetics-api/SOME_PATH");
curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
curl_setopt($ch, CURLOPT_HTTPHEADER, ["x-oanor-key: oanor_test_..."]);
$response = curl_exec($ch);
import requests
r = requests.get(
    "https://api.oanor.com/genetics-api/SOME_PATH",
    headers={"x-oanor-key": "oanor_test_..."},
)
print(r.json())

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