Rfam API
The Rfam database of non-coding RNA families as an API, powered by EMBL-EBI. Rfam groups functional RNAs that share a common evolutionary origin into families, each modelled by a covariance model built from a curated seed alignment and secondary structure. Search the families by name, description or RNA type — riboswitches and other cis-regulatory elements, ribozymes, microRNA families, ribosomal RNAs, transfer RNAs, small nuclear and small nucleolar RNAs, long non-coding RNAs and CRISPR direct repeats — getting each family's Rfam accession, name, description, RNA type and curators; read a family's full record including its description, RNA-type classification, the curators who built it, the number of sequences in its full and seed alignments, the structure source, the curator comment, the clan (group of related families) it belongs to and the Rfam release; and browse the families by RNA class. Ideal for RNA biology, bioinformatics pipelines, non-coding-RNA annotation, comparative genomics and teaching. Family accessions look like RF00005 (transfer RNA). Data from EMBL-EBI Rfam. For protein families and domains see the InterPro API, for protein sequences UniProt, for proteomics datasets PRIDE and for metabolomics MetaboLights.
api.oanor.com/rfam-api
